Supplement Reviews

Discover the Secret Benefits of Milk Thistle for Vibrant Health!

What Is It | Benefits | Side Effects  | Milk Thistle and Pregnancy: Is It Safe | Can It Help with Hangovers | Other Thistle Species | Popular Supplements | Similar Supplements | What Should You Try | Wrapping Up | Warnings And Side Effects | Disclaimer

Are you looking for a natural way to boost your health and vitality? This powerful herbal supplement has been celebrated for centuries for its remarkable benefits, particularly in liver health. Packed with an active compound called silymarin, milk thistle is known to support liver detoxification and regeneration, making it a favorite among health enthusiasts. But the perks don’t stop there! From its antioxidant properties to its potential benefits for digestion and skin health, milk thistle is truly a multi-talented herb.†

In this blog, we’ll explore the fascinating world of milk thistle, exploring its health benefits, potential side effects, and how you can easily incorporate it into your daily routine. Get ready to discover how this little thistle can significantly impact your health!

Section Divider: What Is Milk Thistle

What Is Milk Thistle?

Milk thistle, scientifically known as Silybum marianum, is a flowering herb native to Mediterranean regions. Recognizable by its striking purple flowers and distinctive white-veined leaves, milk thistle has been used for thousands of years in traditional medicine. Its name is derived from the milky white sap that seeps from its leaves when they are broken, and the plant has earned a reputation as a powerful ally for liver health. (1)

milk thistle

The key component of it is silymarin, a complex of flavonoids extracted from the plant’s seeds. Silymarin is believed to be responsible for many of the health benefits, especially its ability to protect liver cells from damage and promote their regeneration. While milk thistle is often celebrated for its liver-supporting properties, its benefits extend beyond just liver health. This herb is also known for its antioxidant effects, which help combat oxidative stress in the body, potentially supporting overall wellness. (1,2,3)

Section Divider: Benefits

Benefits:

Milk thistle offers many health benefits, making it a standout supplement in herbal remedies. Here are some of the most notable advantages:

1. Supports Liver Health:

One of the primary reasons people turn to milk thistle is its remarkable ability to support liver health. Silymarin has been shown to protect liver cells from toxins and promote their regeneration. This makes it a popular choice for those looking to detoxify their liver and improve overall liver function. (1,2,3)


2. Powerful Antioxidant Properties:

Milk thistle is packed with antioxidants, which help combat oxidative stress in the body. These antioxidants neutralize free radicals, potentially reducing the risk of chronic diseases and supporting overall health. (4)


3. Aids Digestion:

In addition to its liver-supporting properties, milk thistle can benefit digestive health. It may help stimulate bile production, which is essential for breaking down fats and absorbing nutrients. This can lead to improved digestion and a more efficient gastrointestinal system. (5,6)


4. Supports Skin Health:

Milk thistle’s antioxidant and anti-inflammatory properties make it beneficial for skin health as well. Some studies suggest it may help reduce acne, improve skin hydration, and even protect against aging. (7,8)


5. May Help Regulate Blood Sugar Levels:

Emerging research suggests that milk thistle might regulate blood sugar levels. Some studies have indicated that silymarin can improve insulin sensitivity and help manage blood sugar levels, making it a potential aid for those with diabetes or metabolic syndrome. (9,10)


6. Promotes Heart Health:

Milk thistle may also contribute to heart health by improving cholesterol levels. Some studies have shown that silymarin can help lower LDL (bad) cholesterol while increasing HDL (good) cholesterol, reducing the risk of heart disease. (11)


7. Potential Weight Management Aid:

While more research is needed, some evidence suggests that milk thistle may assist in weight management. Supporting liver function and improving metabolism could help individuals maintain a healthy weight. (12)

Section Divider: Side Effects of Milk Thistle

Side Effects of Milk Thistle:

While milk thistle is generally considered safe for most people and is well-tolerated, it’s essential to be aware of potential side effects and precautions. Here are some of the side effects you might encounter:

1. Gastrointestinal Issues:

Some individuals may experience digestive discomfort when taking milk thistle. This can include nausea, diarrhea, bloating, or an upset stomach. If you notice any of these issues, consider starting with a lower dose and gradually increasing it as your body adjusts. (13)


2. Allergic Reactions:

In rare cases, people may be allergic to milk thistle or other Asteraceae plants, including ragweed, daisies, and marigolds. Symptoms of an allergic reaction can include itching, rash, or difficulty breathing. Avoiding it altogether is best if you have a known allergy to these plants. (13)


3. Hormonal Effects:

Milk thistle may have estrogen-like effects, potentially affecting hormone levels. This makes it crucial for individuals with hormone-sensitive conditions, such as certain types of breast cancer, to consult with a healthcare professional before use. (9)


4. Drug Interactions:

Milk thistle can interact with certain medications, particularly those metabolized by the liver. This can alter the effectiveness of medications such as statins, anticoagulants, and some anti-seizure drugs. If you’re taking any medications, discussing the use of it with your doctor to avoid potential interactions is essential. (9)


5. Lowered Blood Sugar Levels:

For individuals with diabetes or those taking medications to lower blood sugar, milk thistle may enhance these effects, potentially leading to hypoglycemia (low blood sugar). If you decide to use it in conjunction with diabetes medications, regular monitoring of blood sugar levels is advisable. (9)

Section Divider: Milk Thistle and Pregnancy: Is It Safe?

Milk Thistle and Pregnancy: Is It Safe?

When you’re pregnant, being cautious about what you put into your body is essential, including supplements like milk thistle. While milk thistle is well-known for its liver-supporting and detoxifying properties, its safety during pregnancy isn’t fully understood. Here’s a closer look at why some women consider milk thistle during pregnancy and whether it’s a safe option.


Why Do Women Consider Milk Thistle During Pregnancy?

Some women explore milk thistle as a supplement during pregnancy for several reasons:

  1. Liver Support and Detoxification: Hormonal changes during pregnancy can put extra strain on the liver. Milk thistle’s liver-protective qualities appeal to those seeking natural ways to support liver health during pregnancy. (1,2,3)
  2. Nausea and Morning Sickness Relief: Milk thistle is sometimes used as a remedy for nausea and morning sickness. It may help alleviate pregnancy-related nausea by promoting liver health, though this benefit is mostly anecdotal.†
  3. Digestive Support: Many pregnant women face digestive issues like indigestion or constipation. Milk thistle may help stimulate bile production, improve digestion, and break down fats more efficiently.†
  4. Skin Health: Pregnancy can lead to changes in skin appearance, including acne or dryness. Milk thistle’s antioxidant and anti-inflammatory properties might benefit skin health, naturally supporting clearer, more radiant skin.†
  5. Gestational Diabetes: Although research is limited, some studies suggest that milk thistle may help regulate blood sugar levels. This makes it of interest to women managing gestational diabetes, but its use should always be discussed with a healthcare provider first.†

Is It Safe?

While these potential benefits sound promising, there is not enough research to confirm that milk thistle is safe during pregnancy. Here are a few key points to consider:

  • Lack of Research: Most studies on milk thistle focus on its liver and antioxidant benefits, but there’s little research on its effects during pregnancy. This lack of information makes it hard to determine its safety for pregnant women and their babies.†
  • Hormonal Effects: Milk thistle’s estrogen-like properties could potentially affect hormone levels. This is why women with hormone-sensitive conditions or complications need to avoid using it without a doctor’s approval.†
  • Consult with Your Doctor: If you’re pregnant or planning to become pregnant, it’s critical to talk to your healthcare provider before introducing milk thistle or any supplement into your routine. They can provide personalized guidance based on your individual health needs.†

Section Divider: Can It Help with Hangovers?

Can It Help with Hangovers?

If you’ve ever had one too many drinks, you know the dreaded aftermath of a hangover—headaches, nausea, fatigue, and general discomfort. With milk thistle’s reputation for liver support, you might wonder if it can help ease hangover symptoms. The short answer is it might, but don’t expect it to be a miracle cure. (14)


How Does It Work?

Milk thistle’s active compound, silymarin, is known for protecting and supporting liver function. Since the liver is responsible for detoxifying alcohol and processing it out of your system, keeping your liver healthy can help with recovery from excessive alcohol consumption. Here’s how milk thistle could potentially help:

  1. Liver Protection: Alcohol is tough on your liver, and overindulgence can strain this vital organ. Milk thistle, thanks to its antioxidant and anti-inflammatory properties, may help protect liver cells from the damage caused by alcohol. (1,2,3)
  2. Detoxification Support: Milk thistle promotes detoxification by boosting liver function, helping it process alcohol more efficiently. In theory, this could lead to faster recovery after a night of drinking by flushing out toxins more quickly. (15)
  3. Anti-Inflammatory Effects: Many hangover symptoms, such as headaches and nausea, are linked to inflammation. Milk thistle’s anti-inflammatory effects might help reduce some of the discomfort associated with hangovers. (14)

Can Milk Thistle Prevent a Hangover?

While milk thistle may support liver health and help your body deal with the effects of alcohol, it’s important to manage expectations. Milk thistle won’t prevent a hangover, and it won’t make your symptoms disappear instantly. It might help lessen the severity of some symptoms, but it won’t reverse the effects of alcohol entirely.†

Section Divider: Other Thistle Species

Other Thistle Species:

While milk thistle is the most famous for its health benefits, it’s just one of many thistle species with medicinal properties. Thistles are part of the Asteraceae family, and several species have been used in traditional healing practices. Let’s take a look at some of these species and how they compare to milk thistle.


1. Blessed Thistle (Cnicus benedictus):

Blessed thistle has been used for centuries, primarily for digestive health and stimulating appetite. (16)

blessed thistle

It’s known for:

  • Supporting digestion†
  • Stimulating appetite†
  • Boosting milk production in breastfeeding mothers (17)

Though it shares some similarities with milk thistle, blessed thistle focuses more on digestive and lactation benefits than liver health.†


2. Globe Thistle (Echinops spp.):

Globe thistle is more commonly recognized for its ornamental appeal, but it’s also believed to have mild medicinal benefits. (18,19)

Globe thistle

Traditional uses include:

  • Reducing inflammation†
  • Supporting respiratory health†
  • Easing muscle pain†

However, globe thistle lacks the robust liver-supporting benefits that milk thistle provides.†


3. Artichoke (Cynara scolymus):

Artichoke, a close relative to milk thistle, is primarily known for its edible flower buds and health benefits related to digestion. (21,22)

NATURES-WAY-STANDARDIZED-ARTICHOKE

This extract is used to:

  • Support liver detoxification†
  • Improve digestion†
  • Lower cholesterol†

It contains cynarin, which promotes bile production, making it a great alternative to milk thistle for liver and digestive support.†


4. Scotch Thistle (Onopordum acanthium):

Scotch thistle is a tall, spiky plant often associated with Scotland’s national symbol. (23)

Scotch Thistle

It has been used in traditional remedies to:

  • Promote wound healing†
  • Reduce swelling†
  • Provide anti-inflammatory support†

Although it’s less commonly used in modern supplements, it shares some anti-inflammatory benefits with milk thistle.†


5. Marian Thistle (Silybum marianum):

Marian Thistle

Also known as St. Mary’s Thistle, this species is another name for the milk thistle itself. Marian thistle is recognized by its distinctive white-veined leaves and is famous for its potent liver-protecting properties. The name Marian Thistle is derived from the legend that the white markings on the plant’s leaves were created by the Virgin Mary’s milk, highlighting its strong historical connection to health and healing.†

Section Divider: Popular Supplements

Popular Supplements:

When it comes to supporting liver health and detoxification, plenty of milk thistle supplements are on the market. Each product offers slightly different formulations and additional ingredients, making it important to choose the one that aligns with your health goals. In this section, we’ll explore four popular milk thistle supplements.


Puritan’s Pride Milk Thistle Extract:

Puritans Pride Milk Thistle ExtractPuritan’s Pride Milk Thistle Extract offers a concentrated version of milk thistle with a 4:1 extract ratio. This means you’re getting the equivalent of 1,000 mg of the whole herb in a more potent 250 mg serving. Milk thistle’s active compound, silymarin, is well-known for its liver-protective and antioxidant properties, helping to combat free radicals and promote liver detoxification.†

How To Take Puritan’s Pride Milk Thistle Extract:
The manufacturers recommend that adults take one (1) softgel once or twice daily, preferably with meals.


Hi-Tech Pharmaceuticals Milk Thistle:

Hi-Tech Pharmaceuticals Milk ThistleHi-Tech Pharmaceuticals Milk Thistle packs a potent punch with a standardized 80% concentration of silymarin, the active flavonoid complex known for its liver-protective benefits. The higher concentration of silymarin makes this supplement one of the more powerful options on the market for liver health.†

How To Take Hi-Tech Pharmaceuticals Milk Thistle:
The manufacturers recommend taking 1 tablet twice daily with a meal.


NOW Silymarin Milk Thistle Extract:

NOW Silymarin Milk Thistle Extract

NOW Silymarin Milk Thistle Extract not only provides a strong dose of milk thistle standardized to 80% silymarin, but it also includes turmeric. Turmeric is widely known for its anti-inflammatory and antioxidant properties, adding an extra layer of liver and overall body support. The combination of milk thistle and turmeric creates a synergistic effect. While milk thistle focuses on liver detoxification, turmeric adds inflammation-fighting benefits, making this supplement a powerful duo for comprehensive liver and body health.†

How To Take NOW Silymarin Milk Thistle Extract:
The manufacturers recommend taking 2 capsules 1 to 3 times daily with food. Store in a cool, dry place after opening.


21st Century Milk Thistle Extract:

21st Century Milk Thistle Extract21st Century Milk Thistle Extract offers a standardized concentration of milk thistle in a smaller dose than other products. This supplement is great for those new to milk thistle or for those seeking a low-dose option for daily liver health maintenance. It provides all the core benefits of milk thistle—such as promoting liver detoxification and supporting liver regeneration—without any added ingredients, making it ideal for individuals with simpler supplement needs.†

How To Take 1st Century Milk Thistle Extract:
The manufacturers recommend adults take two (2) capsules daily with any meal or as directed by a healthcare provider. Do not exceed the recommended dosage. Individual results may vary.

Section Divider:

Similar Supplements:

While milk thistle is one of the most popular natural remedies for liver health, there are several other supplements that offer similar benefits. Each of these supplements has unique properties that can support liver function, aid in detoxification, or offer additional health benefits.


Artichoke Extract:

Artichoke extract is often paired with milk thistle for its complementary benefits in promoting liver and digestive health. It contains cynarin, a compound known to increase bile production, which helps the liver break down fats more efficiently and aids in the detoxification process. Additionally, artichoke extract has been shown to help lower cholesterol levels, making it beneficial for both liver health and heart health. (24)

NOW Artichoke Extract

Key Benefits of Artichoke Extract:

  • Supports liver detoxification by stimulating bile production (24)
  • Helps improve digestion, especially after high-fat meals (25)
  • May aid in lowering bad (LDL) cholesterol (26)
  • Contains antioxidants that protect the liver from oxidative stress (27)

Why It Works Well with Milk Thistle: Both milk thistle and artichoke extract support liver detoxification, but while milk thistle focuses on protecting liver cells from damage, artichoke works by stimulating bile production, enhancing the liver’s ability to process fats and toxins.†


Dandelion Root:

Dandelion root is another well-known herb with strong detoxifying properties. It acts as a natural diuretic, helping the body eliminate waste through increased urine output. This assists in flushing out toxins that the liver processes. Additionally, dandelion root is thought to support both liver and kidney health, making it a powerful supplement for whole-body detoxification. (28)

Magnum Drip Dry Diuretic

Key Benefits of Dandelion Root:

  • Acts as a natural diuretic, helping to flush toxins from the body (28)
  • Supports both liver and kidney function (28)
  • Aids in digestion and may help relieve symptoms of bloating or indigestion (28)
  • May help normalize blood sugar levels (28)

Why It Works Well with Milk Thistle: Milk thistle protects the liver from toxins, while dandelion root supports the body’s ability to eliminate those toxins through increased urine production. Together, they form a powerful detox duo, promoting both liver and kidney health.†


Turmeric:

Turmeric, particularly its active compound curcumin, is well-known for its anti-inflammatory and antioxidant properties. Curcumin has been studied for its ability to reduce liver inflammation and protect liver cells from damage caused by toxins. Beyond liver health, turmeric is also widely used to reduce inflammation throughout the body and support overall wellness. (29)

Puritans Pride Turmeric Curcumin

Key Benefits of Turmeric:

  • Reduces liver inflammation and protects liver cells from damage (30)
  • Acts as a powerful antioxidant, fighting oxidative stress (31)
  • Supports joint and cardiovascular health due to its anti-inflammatory effects (32)
  • May enhance liver detoxification processes (33)

Why It Works Well with Milk Thistle: Milk thistle works primarily by regenerating and protecting liver cells, while turmeric can help reduce inflammation and oxidative stress in the liver. Combined, they provide comprehensive liver protection and may even enhance the liver’s natural detox processes.†


Schisandra Berry:

Schisandra berry is an adaptogenic herb used in traditional Chinese medicine to support liver function and boost energy levels. It helps the liver filter and remove toxins more efficiently while also promoting liver regeneration. Schisandra is known for increasing the body’s resistance to stress, helping to balance energy, and promoting overall vitality. (34)

Life Extension Liver Efficiency Formula

Key Benefits of Schisandra Berry:

  • Supports liver detoxification and regeneration (35)
  • Improves energy levels and combats fatigue (36)
  • Acts as an adaptogen, helping the body manage stress (37)
  • Provides antioxidant protection for liver cells (34)

Why It Works Well with Milk Thistle: Schisandra’s adaptogenic properties enhance the body’s ability to handle stress, including the oxidative stress the liver faces. In combination with milk thistle, Schisandra enhances liver detoxification while also boosting energy and resilience, making it an excellent choice for holistic liver support.†


N-Acetyl Cysteine (NAC):

N-acetyl cysteine (NAC) is a precursor to glutathione, one of the body’s most powerful antioxidants. Glutathione plays a critical role in neutralizing free radicals and detoxifying the liver. NAC is often used to help the liver recover from damage caused by toxins such as alcohol, medication, and environmental pollutants. It’s also used in medical settings to treat acetaminophen overdose, underscoring its liver-protective properties. (38)

Hi-Tech Pharmaceuticals NAC

Key Benefits of N-Acetyl Cysteine (NAC):

  • Increases glutathione levels, helping the liver detoxify harmful substances (39)
  • Protects the liver from oxidative stress and toxin damage (40)
  • May help improve respiratory health by thinning mucus in the lungs (41)
  • Supports immune function through its antioxidant activity (42)

Why It Works Well with Milk Thistle: Milk thistle protects and regenerates liver cells, while NAC boosts glutathione levels, giving the liver the antioxidants it needs to neutralize toxins. Together, they offer comprehensive protection and detoxification, making them potent for liver health.†

Section Divider: What Should You Try

What Should You Try:

With so many options available, choosing can feel overwhelming. Each supplement offers unique benefits for liver health and overall wellness, so the best choice depends on your specific goals and health needs. Here’s a breakdown to help you decide which supplement might be right for you.

Ultimately, the right supplement for you depends on your specific goals. If you want overall liver protection, Milk Thistle is a great choice. For those focusing on digestion and cholesterol, Artichoke Extract can be particularly beneficial. If detox and kidney support are priorities, Dandelion Root is your best bet. For those battling inflammation, Turmeric shines as a versatile option. Schisandra Berry is perfect for those who need stress support and an energy boost, while NAC is a potent option for deep detoxification and boosting antioxidant defenses.†

For the best results, you might even consider combining some of these supplements, as they often work synergistically to promote liver health and overall wellness. Always consult with a healthcare professional before starting any new supplement regimen.†

Section Divider: Wrapping Up

Wrapping Up:

And this marks the end of our post on Milk Thistle. Thank you for reading! And as always, if there was something that wasn’t clear, another question you might have, or if you have another idea for a blog, Email Us!

Are you looking for more to read? Check out our other blogs!

Section Divider: Warnings And Side Effects

Warnings And Side Effects:

Keep out of reach of children. Consult a doctor if you are nursing or pregnant prior to use if you are taking any medications, or if you have any medical conditions.

Discontinue use if any allergic or adverse reaction occurs and alert your doctor.

Section Divider: Disclaimer

Disclaimer:

†PLEASE NOTE: The intention of the information provided is for reference only. Furthermore, we are in no way providing medical advice or instruction. Instead, the information provided in this guide/blog utilizes anecdotal information and available studies/reviews. While our goal is to maintain and display accurate information, we can’t guarantee it represents the latest formulation of the product or information. Therefore, please visit the manufacturer’s website if you have any concerns. Also, the information above does not represent our views here at Same Day Supplements. Instead, these are the manufacturers’ and users’ views and information. The Food and Drug Administration has not evaluated these statements. Finally, these products aim not to diagnose, treat, cure, or prevent any disease or illness.

Talib Ahmad Supplement Expert

Talib has been a supplement and fitness enthusiast for over 10 years. He is a passionate powerlifter who enjoys helping others with their supplement regimens and training programs to ensure they achieve the best performance for their goals.