The Science Behind Minoxidil: How Does It Work? (Review & Guide 2024)

March 6, 2023January 19, 2024 Anthony Conigliaro BSc 837 Views

Losing your hair can be a real bummer and can take a toll on your confidence. But don’t worry; there are loads of treatments out there to help combat hair loss, and Minoxidil is one of them! In this blog, we’re going to explore the science behind Minoxidil and how it can help promote hair growth. We’ll also talk about some factors that can affect how well Minoxidil works and give you some tips on how to get the most out of it. So if you’re curious about Minoxidil and how it can help with hair growth, keep on reading!

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What Is Minoxidil:

Minoxidil is a medication that was first developed as a treatment for high blood pressure. However, researchers noticed an unexpected side effect during clinical trials – hair growth. This discovery led to its approval by the US Food and Drug Administration (FDA) as a topical medication for hair loss treatment. This is now a treatment option available over-the-counter and by prescription and is typically used to treat male and female pattern baldness. However, it is important to note that results can vary and may not be effective for everyone. Additionally, it is important to use Minoxidil as directed and to be patient, as it may take several months to see results. (1)

How Does Minoxidil Work? (1,2,3)

Minoxidil is a vasodilator, which means that it works by widening blood vessels and increasing blood flow. When applied topically to the scalp, it widens the blood vessels, increasing blood flow to the hair follicles. This increased blood flow provides the hair follicles with more oxygen and nutrients. As a result, it can help stimulate and prolong hair growth.

Minoxidil also has a direct effect on the hair follicles themselves. The medication activates potassium channels in the hair follicles, which leads to the opening of the cell membranes and an influx of calcium ions. This influx of calcium ions stimulates hair follicles and promotes hair growth.

In addition to its effects on blood flow and hair follicles, Minoxidil may also have an anti-inflammatory effect on the scalp. Inflammation is thought to play a role in hair loss, and reducing scalp inflammation may help promote hair regrowth.

It is important to note that the exact mechanism by which Minoxidil works to promote hair growth is not fully understood. However, research suggests that the medication’s ability to increase blood flow, stimulate hair follicles, and reduce inflammation in the scalp all contribute to its effectiveness in promoting hair growth.

Benefits: (1,2,3)

Some of the benefits of using minoxidil for hair loss include the following:

Regrowing Hair: One of the primary benefits of using minoxidil is that it can help to regrow hair. Studies have shown that minoxidil can effectively regrow hair in men and women with androgenetic alopecia, which is the most common form of hair loss.
Improve Hair Density: Studies have shown that minoxidil can effectively improve hair density in men and women with androgenetic alopecia, the most common form of hair loss. However, the results can vary from person to person, and it may take several months of consistent use before any noticeable improvements are seen.
Slowing Down Hair Loss: In addition to regrowing hair, minoxidil can also help to slow down the process of hair loss. By widening the blood vessels in the scalp, minoxidil can increase blood flow to the hair follicles and help to prevent them from shrinking.

It is important to note that while minoxidil can effectively improve hair health and regrowth, it is not a miracle cure for hair loss. It works best when used as part of a comprehensive hair loss treatment plan that includes a healthy diet, regular exercise, and other hair growth supplements or treatments as recommended by a healthcare professional.

Factors Affecting Minoxidil’s Effectiveness: (4,5)

While Minoxidil can be an effective treatment for hair loss, several factors can affect its effectiveness. Understanding these factors can help individuals maximize Minoxidil’s benefits and achieve better results.

Age: Minoxidil is generally more effective in individuals under 40. This is because our hair follicles become less responsive to growth stimulants, including Minoxidil, as we age.†
The severity of hair loss: Minoxidil is most effective for individuals with mild to moderate hair loss. For individuals with advanced hair loss or baldness, Minoxidil may not be as effective.†
Length of time with hair loss: The longer an individual has been experiencing hair loss, the less effective Minoxidil may be. This is because the longer the hair follicles have been inactive, the harder it is to reactivate them.†
Use of other hair loss treatments: Using other hair loss treatments with Minoxidil, such as finasteride, may increase its effectiveness.†
Consistency of use: Minoxidil must be used consistently and as directed to achieve optimal results. Skipping doses or not using them regularly can reduce their effectiveness.†
Genetics: The effectiveness of Minoxidil can also be influenced by genetics. Individuals with a history of hair loss may not respond as well to Minoxidil as those without a family history.†

Side Effects of Minoxidil:(1,2,4,5)

Minoxidil is generally considered safe for topical use, and most people do not experience any serious side effects. However, like all medications, Minoxidil can cause side effects in some individuals. The most common side effects of Minoxidil include the following:

Scalp irritation: Some individuals may experience mild scalp irritation, including itching, redness, and dryness.†
Increased hair shedding: During the first few weeks of treatment, some individuals may experience an increase in hair shedding. This is a normal part of the hair growth cycle and is a sign that Minoxidil is working.†
Hair growth in unwanted areas (Hypertrichosis): In rare cases, Minoxidil can cause hair growth in areas other than the scalp, such as the face or neck.†
Dizziness: Minoxidil is a vasodilator that can cause blood pressure drop, leading to dizziness in some individuals.†
Chest pain: In rare cases, Minoxidil can cause chest pain or discomfort, which may indicate a more serious cardiovascular issue.†

It is important to note that these side effects are usually mild and go away on their own with continued use of Minoxidil. However, if you experience any severe or persistent side effects, it is important to seek medical attention immediately. Overuse of Minoxidil can increase the risk of side effects and may not provide any additional benefits.

Minoxidil VS Other Hair Loss Treatments:

Several hair loss treatments are available on the market, including prescription medications and over-the-counter products. Here, we will compare Minoxidil to some of the most common hair loss treatments.

Finasteride: Finasteride is a prescription medication that works by blocking the production of dihydrotestosterone (DHT), a hormone that can contribute to hair loss. While both Minoxidil and Finasteride are effective treatments for hair loss, they work in different ways. Minoxidil stimulates hair growth by increasing blood flow to the hair follicles, while Finasteride works by blocking DHT production. (6)
Hair transplant surgery: Hair transplant surgery involves taking hair follicles from a donor area on the scalp and transplanting them to areas with thinning or balding hair. While hair transplant surgery can provide long-lasting results, it is also more expensive and invasive than Minoxidil or other topical treatments. (7,8)
Natural remedies: Many natural remedies and supplements are marketed as treatments for hair loss, such as biotin and saw palmetto. While some of these remedies may have anecdotal evidence to support their effectiveness, there is limited scientific research to confirm their benefits. Minoxidil is backed by decades of research and is one of the few hair loss treatments that are FDA-approved. (9,10,11)

While several treatments are available for hair loss, Minoxidil is one of the most well-researched and effective options. It is also relatively affordable and easy to use compared to other treatments. However, individuals with severe or advanced hair loss may benefit from combining it with other treatments, such as Finasteride or hair transplant surgery, for maximum results.

Who Should Use Minoxidil? (1,2,4,5)

Minoxidil is typically recommended for individuals experiencing hair loss or thinning due to androgenetic alopecia (AGA), the most common type of hair loss. AGA is a hereditary condition that causes hair follicles to shrink and eventually stop producing new hair.

Minoxidil can be used by both men and women and is available in different formulations, including 2% and 5% topical solutions and foams. It is important to note that this treatment option is most effective when used early in the hair loss process. Because of this, it is recommended that individuals start using it as soon as they notice signs of hair thinning or shedding.

While it is generally safe for most people, some groups should exercise caution or avoid using it altogether. These include:

Pregnant or breastfeeding women
Individuals with scalp irritation or sunburn: Minoxidil can irritate the scalp, so individuals with existing scalp irritation or sunburn should avoid using it until their skin has healed.
Individuals with a history of heart disease: Minoxidil is a vasodilator and can lower blood pressure, which can be dangerous for individuals with a history of heart disease.
Some individuals may be allergic to Minoxidil or one of its ingredients, so it is recommended that individuals with a history of allergies consult their doctor before using it.

Overall, Minoxidil is a safe and effective treatment for hair loss. Still, it is important to use it as directed and to be aware of any potential side effects or contraindications. If you have any concerns or questions about whether it is right for you, it is recommended that you consult with your doctor or a healthcare professional.

Can Women Use Minoxidil?

Minoxidil is an effective treatment for hair loss in women. Several clinical studies have shown that Minoxidil can help women regrow hair, especially in cases of androgenetic alopecia (AGA), which is the most common cause of hair loss in women. In one study, 52% of women with AGA who used a 5% Minoxidil solution for 48 weeks showed significant improvement in hair growth, compared to just 11% of those who used a placebo. Another study found that Minoxidil helped to increase hair density in women with AGA after six months of use. (1,12,13)

Here are some tips for using minoxidil for women:

Choose the right strength: Women should use a 2% minoxidil solution, while men typically use a 5% solution. Using a higher strength can increase the risk of side effects.
Apply to dry scalp: Make sure your scalp is dry before applying minoxidil. Use a towel or hair dryer to dry your hair and scalp thoroughly.
Apply twice a day: Apply minoxidil to the affected area of the scalp twice a day, ideally in the morning and at night.
Use the dropper to apply the solution: Use the dropper provided to apply the solution directly to the scalp. Be sure to spread the solution evenly over the affected area.
Massage into the scalp: Gently massage the solution into your scalp with your fingertips for about 1 minute after applying. This helps to distribute the solution evenly and increase absorption.
Wash your hands: Wash your hands thoroughly after applying minoxidil to avoid accidentally spreading it to other parts of your body.
Allow the solution to dry: Allow the minoxidil solution to dry completely before styling your hair or going to bed.
Be patient: It may take several months of consistent use to see results. Don’t give up if you don’t see results right away.

By following these tips, women can use minoxidil safely and effectively to promote hair growth and combat hair loss. However, consulting with a healthcare professional before starting any new treatment is always a good idea.

Alternative To Minoxidil For Hair Growth: (9,10,11)

Natural hair supplements are a popular alternative to prescription treatments like Minoxidil for promoting hair growth and improving hair health. These supplements typically contain vitamins, minerals, and other nutrients important for healthy hair growth, such as biotin, vitamins C, E, and iron. While some evidence suggests that certain supplements may benefit hair growth, the research in this area is limited and often conflicting. Some studies have shown that certain supplements can help to improve hair thickness and reduce hair loss, while others have found no significant benefits.

It is important to note that these alternatives have not been studied as extensively as Minoxidil and their effectiveness may vary from person to person.

There are several alternatives you could utilize for hair growth, including:

Biotin: Biotin is a B vitamin that is essential for hair growth. It can be taken as a supplement or found in certain foods, such as eggs, nuts, and salmon.†

Vitamin D: Vitamin D plays a role in hair follicle growth and can be found in foods like fatty fish, egg yolks, and mushrooms. It can also be taken as a supplement.†

Iron: Iron is an important mineral for hair growth, as it helps to carry oxygen to the hair follicles. A deficiency of Iron is a common cause of hair loss, so supplementing with iron may help to promote hair growth.†

Zinc: Zinc is important for healthy hair growth and may help to prevent hair loss. It is found in oysters, red meat, and pumpkin seeds but can also be supplemented.†

Saw Palmetto: Saw palmetto is an herbal supplement that is commonly used to treat hair loss in men. It works by blocking the production of DHT, a hormone that can contribute to hair loss.†

Omega-3 fatty acids: Omega-3 fatty acids are important for overall hair health and may help to reduce inflammation and promote hair growth. They are found in fatty fish, walnuts, and chia seeds but can also be supplemented.†

L-Arginine: L-arginine is an amino acid important for blood flow and can promote hair growth. It can be found in foods like meat, fish, and dairy products or as a supplement.†

Peppermint oil: Peppermint oil has been shown to promote hair growth and can be applied topically to the skin. To avoid irritation, diluting peppermint oil before applying it to the skin is important.†

Coconut oil: Coconut oil is a natural moisturizer that can help keep the skin and hair healthy. It can be applied topically to the skin to promote hair growth.†

Pumpkin Seed Oil: Pumpkin seed oil is another natural remedy that is believed to be effective in treating hair loss. It is derived from pumpkin seeds, which are rich in nutrients such as vitamins A, K, and E, as well as zinc and omega-3 fatty acids, all of which are important for healthy hair growth. Studies have shown that pumpkin seed oil may effectively treat hair loss, particularly in cases of androgenetic alopecia.†

Rosemary Oil: Rosemary oil is a popular natural remedy for hair loss and is believed to work by stimulating blood flow to the scalp and promoting hair growth. Studies have shown that rosemary oil may effectively treat hair loss, particularly in androgenetic alopecia, the most common form of hair loss in both men and women.†

FAQ:

This section will dive into some of your most frequently asked questions about Minoxidil!

Can I Use Minoxidil For My Beard?
Minoxidil is often used off-label by men who want to increase the density of their beard or promote beard growth. However, it is important to note that Minoxidil is not FDA-approved for use on the face or beard, so it should be used with caution and under the guidance of a healthcare professional.† When using Minoxidil on the beard, it is important to apply it only to the areas where you want to promote hair growth and to avoid getting it on other parts of your face or in your eyes. Minoxidil can cause skin irritation, so you may want to start with a small amount and gradually increase the dose as tolerated.†
How to use Minoxidil for beard growth?
If you have decided to use Minoxidil for beard growth, following the correct application process is important to ensure optimal results and minimize the risk of side effects. Here are some steps to follow: Start with a low concentration: Minoxidil is available in different concentrations, ranging from 2% to 5%. If you’re using it for the first time, starting with a lower concentration (2%) is recommended to minimize the risk of side effects. You can gradually increase the concentration if needed.† Cleanse your face: Wash your face with a gentle cleanser and dry it thoroughly before applying Minoxidil.† Apply Minoxidil: Use a dropper or foam applicator to apply a small amount of Minoxidil to the areas of your beard where you want to promote hair growth. Make sure to apply it directly to your skin and not your beard hair.† Massage the area: Gently massage the Minoxidil into your skin using your fingertips. This will help to increase blood flow to the area and stimulate hair growth.† Allow to dry: Leave the Minoxidil on your face for at least four hours before washing it off. Applying Minoxidil twice a day is recommended, with a minimum of eight hours between each application.† Be patient: It can take several weeks to several months before you start seeing noticeable results from using Minoxidil for beard growth. Be consistent with your application, and don’t be discouraged if you don’t see results right away.† Watch for side effects: Keep an eye out for any side effects, such as skin irritation or unwanted facial hair growth in other areas. If you experience any adverse effects, discontinue use and consult with your healthcare provider.†
Are Minoxidil And Rogaine The Same?
Minoxidil and Rogaine are essentially the same things. Minoxidil is the active ingredient in Rogaine, a brand name for a topical solution used to treat hair loss. In other words, Rogaine is simply a brand name for Minoxidil.† Other brands of Minoxidil include the following: Kirkland Minoxidil Member’s Mark Minoxidil BosleyMD Women’s Minoxidil
Are Results Permanent?
Minoxidil results are typically not permanent. Minoxidil works by stimulating hair growth and increasing the size of hair follicles, which can improve the thickness and density of hair. However, once you stop using Minoxidil, the effects will fade over time, and your hair may return to its previous state.† The exact amount of time that the effects of Minoxidil will last can vary from person to person. Some individuals may experience long-lasting results, while others may see their hair begin to thin again relatively quickly after stopping Minoxidil. † It is important to note that Minoxidil is a maintenance treatment, meaning that you must be consistent to maintain its benefits. If you stop using Minoxidil, your hair loss may resume, and it may take several months or more to regain the previously experienced benefits.†
Can It Cause Acne?
Yes, Minoxidil can cause acne as a potential side effect. Acne is a common side effect of Minoxidil use, which may relate to the increase in blood flow to the scalp. This increased blood flow can lead to clogged pores and acne breakouts.† To reduce the risk of acne or other skin problems associated with Minoxidil use, it is important to follow the application instructions carefully and to avoid applying more than the recommended amount. It is also important to keep the scalp clean and avoid using other hair products that could clog pores or cause skin irritation.†
Can It Cause Headaches?
Headaches are a rare side effect of Minoxidil use, but they can occur in some people. The exact cause of headaches from Minoxidil is not well understood. However, studies suggest it may relate to the drug’s effects on blood pressure and blood flow.†
Does It Weigh Your Hair Down Or Make Hair Greasy?
As a liquid solution applied directly to the scalp, Minoxidil may make some people’s hair appear greasy or weighed down. This can be due to the ingredients in the solution, such as propylene glycol, which can have a greasy texture.† However, not everyone who uses Minoxidil will experience greasy or weighed-down hair. Many people find that their hair looks thicker and fuller after using Minoxidil, possibly due to the increased blood flow to the scalp.† Use Minoxidil sparingly and ensure the scalp and hair are completely dry before applying the solution to minimize the greasy appearance of your hair. It may also be helpful to use a gentle, sulfate-free shampoo and to avoid using other hair care products that can weigh down the hair.†

Shipping Minoxidil Worldwide:

Shipping Minoxidil worldwide is a common concern for those who want to use this product but reside in a different country. While Minoxidil is available over the counter in many countries, some areas are not easily accessible. For example, in Canada, Minoxidil 2% is available for purchase without a prescription. However, higher dosages, such as 5%, require a prescription. The good news is that according to The Drug and Health Product Register, Minoxidil imports to Canada are except when sold in preparations for topical use in concentrations of 5% or less. (14) Additionally, at Same Day Supplements, we ship worldwide.

However, we recommend you check with your country’s Customs office to see if your country allows the shipment of this product and provide us with any information necessary to ensure successful delivery to you. This can include information on the declaration, formatting for the shipping label, or additional information for customs.

Looking for more information about importing supplements? Check out our international pages! Or contact us here.

Wrapping Up!

And this marks the end of our post on Minoxidil. Thank you for reading! And as always, if there was something that wasn’t clear, another question you might have, or if you have another idea for a blog, Email Us!

Are you looking for more to read? Check out some of our other blogs!

Warnings And Side Effects:

For external use only. For use by men only. Flammable: Keep away from fire or flame.

It may be harmful if used when pregnant or breastfeeding. Keep out of reach of children. If swallowed, get medical help or contact a Poison Control Center immediately. Stop using and ask a doctor if:

Chest pain, rapid heartbeat, faintness, or dizziness occurs
Sudden, unexplained weight gain occurs
Your hands or feet swell
Scalp irritation or redness occurs
Unwanted facial hair growth occurs
You do not see hair regrowth in 4 months

Products in this blog are not manufactured or distributed by Johnson and Johnson Healthcare Products, Men’s Rogaine Extra Strength distributor.

Disclaimer:

†Please note the intention of the information provided is for reference only. Furthermore, we are in no way providing medical advice or instruction. Instead, the information provided in this guide/blog utilizes anecdotal information and available studies/reviews. While we aim to maintain and display accurate information, we can’t guarantee it represents the latest product formulation or information. Therefore, please visit the manufacturer’s website if you have any concerns. Also, the information above does not represent our views here at Same Day Supplements. Instead, these are the manufacturers’ and users’ views and information. Additionally, the Food and Drug Administration has not evaluated these statements. Finally, these products aim not to diagnose, treat, cure, or prevent disease or illness.