Synadrene By Hi-Tech Pharmaceuticals (Review)

June 11, 2024 Talib Ahmad Supplement Expert 2164 Views

When it comes to your weight loss journey, picking the right fat burner can be what takes your results to the next level. But knowing what to look for isn’t always simple, especially when formulas change often. Fortunately, that’s why we’re here! In this post, we’re going over Synadrene by Hi-Tech Pharmaceuticals, and we’ll cover some popular faqs, like what’s changed since it was released in 2016.

What is Synadrene?

Synadrene by Hi-Tech Pharmaceuticals is a top-class fat burner that replicates a discontinued fat burner, Metabolic Nutrition’s Synedrex. Similar to Synedrex, Synadrene had a revision from a version with the addition of 1,3-Dimethylamylamine HCL (DMAA) to 2-Aminoisoheptane (DMHA). Synadrene can be used by anyone looking to burn some extra calories, get that extra edge in their routine, shed fat, maintain muscle, or have more energy during the day.†

The Original Synadrene Ingredients:

The B vitamins may help increase your energy. Whereas chromium can help insulin transport glucose into cells, which in turn is used for energy.†

Vitamin B12
Vitamin B3
Chromium
Vitamin B6

Synadrene Proprietary blends:

Methylxanthine
Green Tea Extract
DMAA
Sulbutiamine
Sandalwood Extract
Yohimbine Extract
Alpha Lipoic Acid
Poly-Thyronine

Methylxanthine is a mild stimulant that includes caffeine, theophylline, and theobromine. (1) Unfortunately, this version of Synadrene doesn’t state what type of stimulant Methylxanthine is. However, it is often used in dietary supplements, representing caffeine on the label. The next ingredient, Green Tea Extract, is a very potent antioxidant. It also acts as a thermogenic, increasing thermogenesis in the body. (2)

Next is the 1,3-dimethylamylamine HCl (DMAA), which is a strong stimulant. With the DMAA, you’ll notice increased energy and focus. (3) Sulbutiamine is a great nootropic and also an appetite suppressant. It also really helps with alertness, tackling that “brain fog” feeling. (4)

Sandalwood Extract may help with muscle cramping and shows promise as an anti-diabetic (5). Yohimbine Extract may help with stubborn fat areas by increasing fat utilization (6). Alpha Lipoic Acid (ALA) is another antioxidant. Studies suggest that ALA may have some anti-obesity properties, which may result in some weight loss. (7) Finally, Poly-Thyronine is a combination of thyroid hormone metabolites T2. In terms of fat loss, this ingredient may boost metabolism and reduce appetite (8).

Why Remove DMAA?

In August 2018, DMAA was no longer considered a dietary supplement by the US FDA. Therefore, products containing it had to be reformulated. (9) Synadrene wasn’t the only product affected by this change. Other popular fat burners like Hydroxyelite and Lipodrene were also reformulated along with changes in pre workouts like Mesomorph.

If you’d like to read more about the change and DMHA, check out our blog HERE!

Synadrene Now:

This formula features:

Caffeine
Green Tea Extract
2-Aminoisoheptane HCl (DMHA)
Walnut Extract
Sulbutiamine
Sandalwood Extract
Yohimbe Extract
Alpha Lipoic Acid
Poly-Thyronine.

As you can see, most of the ingredients stayed the same after the change. In fact, the only formula change is the addition of DMHA and Walnut Extract and the removal of DMAA. Visually, we can also see that the methylxanthine has been changed to caffeine. But overall, the ingredient blends and milligrams are the same across the versions. DMHA is actually sourced from the walnut tree, so by including both DMHA and Walnut Extract in Synadrene, the effects of DMHA may be amplified. (10)

Synadrene Benefits:

Synadrene is a high-stim fat burner. Because of this, many of the benefits you may experience stem from the stimulant. Those benefits can include increased energy, mood/focus boost, improved metabolism, and appetite suppression. Based on our customer feedback, the most prominent effect of Synadrene in 2024 is appetite suppression!

Of course, individual results and effects will vary, but let’s check out some customer feedback, too!

Synadrene Reviews:

Customer Review By Billy B.: “Good product, I like it.”

Customer Review By Stuart: “I’ve used this product before a few years back and unlike other products it’s good to see it hasnt changed! For me it kicks in within 15-20mins that Yohimbe has a feeling of its own! Then my alertness begins to become very acute followed by a sharp increase of mental focus. Within 45mins thermogenesis starts to ramp up and your body starts warming up and for me it’s pretty intense I start to get a nice glycining sweat on. The energy levels are fantastic and within an hour or so I’m amping whether it’s at the gym or working a 12 hour day this product on average for me 102kg 6.1ft tall last 6 – 8 hours. I’ve stopped taking preworkout as this works just as well.

For me the hardest part is getting motivated to get to the gym once I’m there ill put in the work so this product helps motivate me to get out of the house and get it done. My reason for purchasing was to drop weight. I’m 102kg and plan to hit at least 90kg in 3 months. I have been 88kg before that is the goal but I’m happy if I hit 90kg for my height. Where this really helps is appetite suppression it might be the chromium but more so the combination of all the ingredients you have to force yourself to eat.

So for me the snacks have disappeared from my day as I don’t need them and I find my servings are smaller because I don’t feel hungry. I have force two small meals because I’m seeing the energy I’m burning on this stuff so need to put fuel in there some how. Last but not least I won’t take this product after 12pm once I took it at 4pm and couldn’t sleep unassisted. So normally 10am or 12pm works for me if it’s a gym day might take an RTD with only 100mg of caffeine or less but don’t need it. DID I MENTION …. this on one pill ! Directions say 3 pills a day no more than 4 in 24hrs I would never take that I took 2 caps together at the start because I didn’t read the bottle and that was scary. I bought the 3 x bottles got the discounted price so that will give approx 3 months supply so I’ll review again in 3months on the weight loss journey.

Highly Recommend I’m from NZ and we don’t sell this here anymore. Shout out to Same Day Supplements who got my product to me in 5 days flat. That’s 3 business days excluding the weekend as I orders on a Friday. Best service and communication from them that I have had from any company. Never ordered from them before so was worried it wouldn’t arrive for a month if at all. This is my go to Supplement company now it takes 4 days to get an order from within NZ so the delivery service it outstanding. I’m on the website looking for more deals as well speak.”

Customer Review By Jessica: “Strong but works great. No appetite. Plenty of energy to kill your workout.”

How To Take It:

The manufacturers recommend taking 1 capsule three times daily. Do not exceed 4 capsules in any 24 hours.

Similar To Synadrene:

For starters, if you like Synadrene, you may find Synedrex from Metabolic Nutrition to be a good alternative. Read more about Synedrex HERE!

For a more thermogenic-focused fat burner, check Lean EFX or Psychotic Diablo
If you felt Synadrene wasn’t stimulant-heavy enough for you, check ECA Xtreme or Her Ab Ignitor
Or, if you thought Synadrene was too strong for you, check out HyperCuts or Raze

Synadrene VS Hydroxyelite:

As we mentioned previously, Hydroxyelite and Synadrene were both affected by the removal of DMAA and as a result both formulas now contain DMHA. Like Synadrene, Hydroxyelite is often famed for it’s appetite suppression properties. So which Hi-Tech fat burner is better?

Above we have the label for the current version of Hydroxyelite. If you’d like to read more about Hydroxyelite’s previous formula click HERE. Or about how it compares to Oxyelite Pro, click HERE.

From the label, we see Hydroxyelite contains:

Bauhinia Extract
Bacopa Extract
Walnut Bark Extract
Cirsium Oligophyllum Extract
Rauwolscine Extract
Garcinia Cambogia Extract
DMHA
Caffeine

When compared to Synadrene, 3 ingredients are directly shared; Caffeine, DMHA, and Walnut Bark Extract. There is also a similar fourth ingredient pair: Yohimbe and Rauwolscine.

Rauwolscine is actually a metabolite of Yohimbine, which works mainly by blocking alpha-2 adrenergic receptors located in fat cells. Once yohimbine has bound with a fat cell, it “turns off” the alpha receptor, which allows the fat cells to mobilize and burn off. (12)

The other ingredients in Hydroxyelite dive into categories like thermogenesis, mood/focus, and appetite suppression.†

Is Hydroxyelite Better?

After comparing the labels and reviews, we would say Hydroxyelite may be better for individuals seeking a potent appetite suppressant. However, we would expect Synadrene to better suit individuals looking for a fat burner to promote energy and thermogenesis. Lastly, we would expect the focus and mood-boosting properties of ingredients like Bacopa Extract to be more prominent in Hydroxyelite.†

If you’re looking for an alternative to these fat burners or a better appetite suppressant, we recommend checking out Methyldrene Elite.

For information on how Hydroxyelite and Methyldrene Elite compare, check out our blog!

Wrapping Up!

This concludes our comparison of Synadrene. Thank you for reading, and if you have any questions, need a recommendation, or have a topic you want us to cover in a future blog, let us know HERE!

Meanwhile, if you are looking for more to read, check out some of our other blogs!

For more information on the previous version of Synadrene, check out Trainer Joe B’s Video!

Side Effects And Warning:

Not for use by individuals under the age of 18 years. Do not use it if you are pregnant or nursing. This product can raise blood pressure and interfere with other drugs you may be taking. Talk to your doctor about this product. Individuals who consume caffeine with this product may experience serious adverse health effects. Individuals who are sensitive to the effects of caffeine should consult a licensed healthcare professional before consuming this product.

Do not consume synephrine or caffeine from other sources, including but not limited to coffee, tea, soda, or other dietary products or medications containing caffeine or phenylephrine. Do not use it for more than 8 weeks.

Consult with your physician prior to use if you are taking medication, including but not limited to MAOI inhibitors, Aspirin, antidepressants, nonsteroidal anti-inflammatory drugs, or products containing phenylephrine, ephedrine, pseudoephedrine, or other stimulants.

Consult your physician prior to use if you have a medical condition, including but not limited to heart, liver, kidney, or thyroid disease, psychiatric or epileptic disorders, difficulty urinating, diabetes, high blood pressure, cardiac arrhythmia, recurrent headaches, enlarged prostate, or glaucoma.

Discontinue 2 weeks prior to surgery or if you experience rapid heartbeat, dizziness, severe headache, or shortness of breath. In case of accidental overdose, seek professional assistance or contact a poison control center immediately.

Avoid alcohol while taking this product. Exceeding recommended serving may cause serious adverse health effects, including heart attack and stroke. Improper use of this product may be hazardous to a person’s health.

This product may contain ingredients that are banned by some sports organizations and/or increase the risk of false positives on a drug test. Please consult with your sports organization or physician before taking this product.

Disclaimer:

†Please note the intention of the information provided is for reference only. Furthermore, we are in no way providing medical advice or instruction. Instead, the information provided in this guide/blog utilizes anecdotal information and available studies/reviews. While we aim to maintain and display accurate information, we can’t guarantee it represents the latest product formula or information. Therefore, please visit the manufacturer’s website if you have any concerns. Also, the information above does not represent our views here at Same Day Supplements. Instead, these are the manufacturers’ and users’ views and information. Additionally, the Food and Drug Administration has not evaluated these statements. Finally, these products aim not to diagnose, treat, cure, or prevent disease or illness.